Another significant factor in the gut-skin connection is a condition called leaky gut, or increased intestinal permeability. The gut lining acts as a barrier, regulating the passage of nutrients while preventing harmful substances from entering the bloodstream. However, when the integrity of the gut lining is compromised, toxins, undigested food particles, and bacteria can leak into the bloodstream, triggering an immune response and promoting inflammation throughout the body.

Research suggests that individuals with psoriasis often have higher levels of intestinal permeability compared to those without the condition. This leaky gut phenomenon contributes to systemic inflammation, exacerbating psoriasis symptoms. By addressing leaky gut and reducing inflammation in the gut, we can indirectly alleviate the inflammation in the skin, leading to improvements in psoriasis.